Summary of Published Literature Supporting the Use of Hypertension Relief Device for Lower Blood Pressure
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Most of the research has been done on a pre-hypertensive or low first stage hypertensive population. This leads one to observe that the significant drops in both populations are impressive. When the device is used with second stage hypertensive the end results remain similar, dropping most patients into the pre hypertensive range over a period of 6-8 weeks. Research is ongoing and trends indicate further usefulness in difficult populations such at Type 2 diabetics.
This guarantee is only valid when the device is used properly, 12 minutes a day at least 5 days a week for 7 weeks. If you do not see a reduction in your blood pressure after 7 weeks you may call Customer Service (within 60 days of purchase) to obtain a return authorization code.
Improvement in ANS and Endothelial Dysfunction
Improved Vagal Function
The current body of evidence suggests that a major factor leading to hypertension is massive switch in the Autonomic Nervous System (ANS). The sympathetic nervous system (SNS) (commonly referred to as the fight and flight function) tends to increase in prevalence while the Parasympathetic Nervous System (PNS), (which can be thought of as the body's braking or relaxation system) tends to decrease.
Researchers believe one of the main factors behind the significant blood pressure reductions achieved by those using the device occur because of a massive switch in this nervous system function. Those who have benefited from this therapy see an improvement in vagal tone and a decrease in sympathetic activity in the ANS. This change results in a more efficient and better operating cardiovascular system, opens up restricted arteries and improves blood flow throughout the body.
Improvement in Endothelial Dysfunction
"Acute vascular responses to isometric handgrip exercise and effects of training in persons medicated for hypertension", American Journal of Physiology: Heart and Circulatory Physiology, 2006
Endothelial Dysfunction is a precursor or marker of further cardiovascular risks. This condition is characterized by the inability of the arteries and arterioles to fully dilate. The consequence is a systemic restriction of blood flow to peripheral tissues in the body, which results in an overall hypertensive condition in the body.
According to McGowen, et. al., there is an apparent improvement in endothelial dysfunction when hypertensive individuals employ isometric handgrip therapy. Isometric handgrip training improves vasodilatation of individuals who suffer from endothelial dysfunction. The effects of this training protocol are similar to aerobic exercises like running, biking and swimming.
The device, in which this isometric handgrip therapy is embodied, may reduce the cardiovascular risks associated with those who suffer from endothelial dysfunction. Endothelial improvement is associated with lower occurrences of cardiovascular disease (CVD), heart failure, Peripheral Artery Disease (PAD), diabetes, hypertension and other cardiovascular risks.
Medicated Hypertensive Population
"Isometric handgrip training improves local flow-mediated dilation in medicated hypertensives" European Journal of Physiology, 2007
The scope of this study was primarily to determine the mechanisms that actually cause the reduction of blood pressure when using this therapy. The researchers indicate they believe that this therapy can be used as an effective tool in the management of hypertension. The device may be used to reduce potential risks associated with "...stroke, coronary artery disease and mortality..." that accompany uncontrolled blood pressure.
In addition, participants in this study saw significant reduction in blood pressure-with the average drop at 15.4 mmHg. These results are consistent with previous studies regarding this therapy.
Isometric training lowers resting blood pressure and modulates autonomic control" Medicine and Science in Sports and Medicine, 2003
Medicated participants in this study had an average drop of 19 mmHg systolic and 7 mmHg diastolic blood pressures. Results indicate that the device is an effective treatment for medicated, individuals.
Researchers also indicate that the very fact that the device is simple, convenient and easy to perform it should have significant impact in the future treatment of hypertension.
"Isometric handgrip training improves blood pressure and endothelial function in persons medicated for hypertension", and "Isometric handgrip training improves blood pressure and endothelial function in persons medicated for hypertension", The American Physiological Society, The APS Intersociety Meeting, October 2004.
Further evidence was presented to the body of the Annual Meeting of the American Physiological Society, in two separate presentations, that medicated individuals saw significant drops in blood pressure.
The first presentation compared the results between users and those performing an Isometric Leg Press (ILP). Those using this therapy saw an average drop of 7.9 mmHg while the ILP group had no measurable drop.
The second presentation concluded that those using the training saw average drops systolic blood pressure of 15.3 mmHg. Request your free copy of this report.
"Brief Report: Regular Isometric Handgrip Training Lowers and Controls Blood Pressure in Hypertensive Patients: 4 One Year Cases," Independent Study, Harry I. Geisberg, M.D., Primary Care Associates, Anderson, SC.
This independent clinical study tracked medicated hypertensive patients over a one-year period and the results were impressive. The average drop in Systolic blood pressure was 30.75 mmHg and the average diastolic drop was 16 mmHg. The treating physician was able to remove several patients completely from their medication.
Dr. Geisberg was able to use this therapy, effectively, with patients in his primary care office. His conclusion was that this therapy is a tool that can be implemented in family practice environment.
Non-medicated Population
Normotensive
The effects of isometric exercise training on resting blood pressure and orthostatic tolerance in humans", Experimental Physiology 2002
A group of patients who had normal blood pressure underwent the handgrip therapy, embodied in the device. The results were positive-average blood pressure readings dropped from 120 mmHg SPB to 110 mmHg SBP. The therapy further improved the healthy levels of blood pressure that these individuals maintained.
This study shows that this therapy causes blood pressure reduction in healthy people, proving that the therapy is viable, safe and effective method for hypertensive and pre-hypertensive patients.
"Isometric handgrip training reduces arterial pressure at rest without changes in sympathetic nerve activity", American Journal of Physiology: Heart and Circulatory Physiology, 2000.
Ray and Carrasco tested a group of healthy individuals whose resting blood pressures were on average 116 mmHg systolic and 67 mmHg diastolic-well below the standard of healthy blood pressures recommended by healthcare professionals and researchers.
At the conclusion of the test subjects resting systolic blood pressure has dropped a notable 3 points from 116 mmHg to 113 mmHg. The diastolic blood pressure reductions were far more significant. The average drop was from 67 mmHg to 62 mmHg. A five point drop in already healthy individuals diastolic blood pressure.
Hypertensive
"Short-term isometric exercise reduces systolic blood pressure in hypertensive adults: possible role of reactive oxygen species, International Journal of Cardiology, 2006
Researchers at the University of Miami Ohio were able to record a positive change in the lipid profile of those performing this therapy. Users of the device saw a decrease in LDL cholesterol and an increase in HDL levels. These findings are similar to results found by those who perform regular aerobic exercise.
While the purpose of this study was to determine a mechanism of action for this therapy, it should be noted that the average participant in this study saw an average systolic drop in blood pressure of 13 mmHg.
These results indicate that this therapy is an effective treatment for hypertension and related cardiovascular diseases.
"Isometric exercise training lowers resting blood pressure", Medicine and Science in Sports and Exercise, 1992
This study was one of the introductory investigations of the findings of the IHG protocol. Those test subjects who followed the isometric protocol, to that found in the device, had an average blood pressure drop of 12.5 mmHg systolic, and 14.9 mmHg diastolic. This study was significant in that it opened the investigations regarding the use of IHG as an effective means of blood pressure management.
See: Taylor, A. C., McCartney, N., Kamath, M. V., & Wiley, R. (2003). Isometric training lowers resting blood pressure and modulates autonomic control. Med Sci Sports Exerc, 35(2), 251-256; Wiley, R. L., Dunn, C. L., Cox, R. H., Hueppchen, N. A., & Scott, M. S. (1992). Isometric exercise training lowers resting blood pressure. Med Sci Sports Exerc, 24(7), 749-754; Howden, R., Lightfoot, R.T., Brown, S.J., and Swaine, I.L. (2002)
The effects of isometric exercise training on resting blood pressure and orthostatic tolerance in humans. Exp Physiol., 87: 507-515.
McGowan CL, Levy AS, Millar PJ, Guzman JC, Morillo CA, McCartney N, Macdonald MJ. Acute vascular responses to isometric handgrip exercise and effects of training in persons medicated for hypertension. Am J Physiol Heart Circ Physiol 291: H1797-H1802, 2006.
Ibid.
McGowan CL, Visocchi A, Faulkner M, Verduyn R, Rakobowchuk M, Levy AS, McCartney N, Macdonald MJ. Isometric handgrip training improves local flow-mediated dilation in medicated hypertensive. Eur J Appl Physiol. 2007 Feb;99(3):227-34. Epub 2006 Nov 15.
Taylor, A. C., McCartney, N., Kamath, M. V., & Wiley, R. (2003). Isometric training lowers resting blood pressure and modulates autonomic control. Med Sci Sports Exerc, 35(2), 251-256.
"Isometric handgrip training improves blood pressure and endothelial function in persons medicated for hypertension", Cheri L.M. McGowen, Adrienne Visocchi, Martha Faulkner, Mark Rakobowchuk, Neil McCartney, Maureen J. MacDonald, The American Physiological Society, The APS Intersociety Meeting: Integrative Meeting-Abstracts of Invited and Contributed Presentation, http://www.the-aps.org/publications/tphys/2004html/AugTPhys/IBEabstracts.pdf, Pg. 15, 6.3;
Geisberg, H. I., (1998). Brief Report: Regular Isometric Handgrip Training Lowers and Controls Blood Pressure in Hypertensive Patients: 4 One Year Cases. Independent Study, Harry I. Geisberg, M.D., Primary Care Associates, Anderson, SC.
Howden, R., Lightfoot, R.T., Brown, S.J., and Swaine, I.L. (2002)
The effects of isometric exercise training on resting blood pressure and orthostatic tolerance in humans. Exp Physiol., 87: 507-515.
Ray, C., & Carrasco, D. (2000). Isometric handgrip training reduces arterial pressure at rest without changes in sympathetic nerve activity. Am J Physiol Heart Circ Physiol, 279, H245-H249.
Peters PG, Alessio HM, Hagerman AE, Ashton T, Nagy S, Wiley RL. Short-term isometric exercise reduces systolic blood pressure in hypertensive adults: possible role of reactive oxygen species. Int J Cardiol. 2006 Jun 16;110(2):199-205. Epub 2005 Oct 18.
Wiley, R. L., Dunn, C. L., Cox, R. H., Hueppchen, N. A., & Scott, M. S. (1992). Isometric exercise training lowers resting blood pressure. Med Sci Sports Exerc, 24(7), 749-754.
*NOTE: You should not start this or any other exercise program without first consulting your doctor. To protect yourself from injury you must read all of the information contained in the owner's manual before using this device. Do not discontinue prescribed medications without consulting your physician.
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